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Real Madrid vs. Barcelona prediction, odds, time: 2024 La Liga picks, El Clasico best bets for April 21

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A bitter rivalry is set to renew on Sunday when Real Madrid battles Barcelona in the latest edition of El Clásico. Real Madrid (24-6-1) are coming off a 1-1 draw with Manchester City on Wednesday, but earned the win on a 4-3 edge in penalty kicks to advance to the UEFA Champions League semifinals. Barcelona (21-7-3), meanwhile, saw their run in the UEFA Champions League come to an end on Tuesday with a 4-1 loss to Paris Saint-Germain. Real Madrid have won six of the last eight La Liga matches with Barcelona.

Kickoff is set for 3 p.m. ET at Santiago Bernabeu Stadium in Madrid, Spain. Real Madrid are listed as the -130 favorites (risk $130 to win $100) in its latest Real Madrid vs. Barcelona odds, with Barcelona the +300 underdogs. A draw is priced at +290 and the over/under for total goals scored is 3.5. Before locking in any Barcelona vs. Real Madrid picks or El Clasico predictions, you need to see what proven SportsLine soccer expert Jon “Buckets” Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup and much more. In 2023, he was red-hot, going 248-234-12 for a profit of $2,593 for $100 bettors. That included an 86-59-5 record in the Premier League for a $3,463 profit. Anyone who follows him is way up.

Now, Eimer has broken down Real Madrid vs. Barcelona from every angle and identified his picks La Liga predictions. You can head to SportsLine now to see Eimer’s picks. Here are the betting lines and trends for Barcelona vs. Real Madrid:

  • Real Madrid vs. Barcelona over/under: 3.5 goals
  • Real Madrid vs. Barcelona money line: Real Madrid -130, Draw +290, Barcelona +300
  • Real Madrid vs. Barcelona spread: Real Madrid -0.5 (-130)
  • RM: Leads the Spanish La Liga with 67 goals scored
  • BAR: Have a plus-28 goal differential in league play
  • Real Madrid vs. Barcelona picks: See picks here

Why you should back Real Madrid 

Rodrygo has been on a tear. He has scored five goals in his past four matches, including a goal in Wednesday’s match at Manchester City. He scored both goals in the 2-0 victory over Athletic Club in La Liga action on March 31. For the season, he has 30 appearances, including 25 starts, with 10 goals and five assists on 77 shots with 31 on target.

Forward Joselu is also among Real Madrid’s top offensive performers. In 29 La Liga appearances, including 11 starts, the 34-year-old has registered eight goals and two assists on 51 shots, including 22 on target. He had two shots, including one on net in the 1-0 win at Mallorca on April 13. His last league goal came in a 1-1 draw at Rayo Vallecano on Feb. 18. See which team to pick here.

Why you should back Barcelona

Veteran forward Robert Lewandowski powers the offense. In 28 appearances in La Liga play, including 25 starts, Lewandowski has registered 13 goals and eight assists on 80 shots with 31 on target. In a 3-0 victory at Atletico Madrid on March 17, he scored one goal and added two assists on three shots, including one on target. The 35-year-old from Poland has had three two-goal efforts on the season, the last coming in a 2-1 win at Celta Vigo in February.

Forward Joao Felix has registered seven goals and three assists in 24 appearances, including 18 starts. Felix has taken 51 shots, including 21 on target. The 24-year-old from Portugal has been on a roll of late in La Liga play. He had a goal on three shots in a 1-0 win at Cadiz on April 13. He had an assist in the 1-0 win over Las Palmas on March 30, and scored a goal in the 3-0 win over Atletico Madrid on March 17. See which team to pick here.

How to make Real Madrid vs. Barcelona picks

Eimer has broken down Sunday’s El Clasico matchup from every possible angle and is going Under on the goal total, and has locked in another confident best bet and a full breakdown of this match. He’s sharing his El Clasico picks and analysis only at SportsLine.

So who wins Barcelona vs. Real Madrid on Sunday, and where does all the betting value lie? Visit SportsLine now to see which wagers have all the value, all from the soccer expert who was up almost 26 units on all soccer picks in 2023, and find out.

How to get in-depth soccer coverage daily

The CBS Sports Golazo Network has you covered with soccer news, highlights, analysis, and exclusive games. The 24-hour digital network provides around-the-clock soccer viewing to fans across the country, including morning shows and live matches. It launched in April and has been a smashing success thus far, expanding its offerings every week. Watch the CBS Sports Golazo Network now here.

The CBS Sports Golazo Network provides soccer fans with wall-to-wall coverage of the most popular game in the world. Check it out now on CBSSports.com, the CBS Sports app for connected TV devices, the CBS Sports mobile app, Pluto TV or Paramount+.

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